대구가톨릭대학교 약학대학

1992. 3. - 1999. 2.

이학사, 수원대학교 공과대학 유전공학과

1999. 3. - 2001. 2.

약학석사, 서울대학교 Thesis title: Signal transduction pathway during lovastatin-induced apoptosis (Supervised by Dr. Seung-Ki Lee)

2001. 3. - 2007. 2.

약학박사, 서울대학교 Thesis title: Identification of Cdk2 target molecules and functional roles during apoptotic cell death (Supervised by Dr. Seung-Ki Lee)

2004. 3.-2005. 2.

연구원 서울대학교 종합약학연구소

2007. 3.-2009. 2.

연수연구원 서울대학교 BK21 응용생명약학사업단

2009. 3.-2013. 9.

연구교수 고려대학교 생명자원연구소

2010. 9.-2011. 2.

강사 세종대학교 생명공학부

2013. 10.-2014. 2.

선임연구원 서울대학교 종합약학연구소

2014. 3.-2014. 8.

연구조교수 서울대학교 생명공학공동연구원

2014. 9.-현재

조교수 대구가톨릭대학교 약학대학 약학부

국제학술지 1

Choi JS, Chun KS, Kundu J, Kundu JK. Biochemical basis of cancer chemoprevention and/or chemotherapy with ginsenosides (Review). Int J Mol Med. (2013) 32(6):1227-38.

국제학술지 2

Choi JS and Lee CK. Maintenance of cellular ATP level by caloric restriction correlates chronological survival of budding yeast. Biochem Biophys Res Commun. (2013) 439(1):126-31.

국제학술지 3

Choi JS, Oh JI, Na M, Lee SK, Joo SH. PKCδ promotes etoposide-induced cell death by phosphorylating Hsp27 in HeLa cells. Biochem Biophys Res Commun. (2012) 426(4):590-5.

국제학술지 4

Lee JS, Kim WS, Kim JJ, Chin YW, Jeong HC, Choi JS, Min HG, Cha HJ. Identification of anti-melanogenic natural compounds from Galega officinalis and further drug repositioning. J Dermatol Sci. (2012) 67(1):61-3.

국제학술지 5

Choi JS*, Choi KM*, Lee CK. Caloric restriction improves efficiency and capacity of the mitochondrial electron transport chain in Saccharomyces cerevisiae. Biochem Biophys Res Commun. (2011) 409(2):308-14. (*: co-first author)

국제학술지 6

Choi JS, Shin HY, Kwon KS, Shin S, Choung SY, Kwon YS, Lee JW, Choi BH, Lee CK. Effects of Oxypeucedanin on Global Gene Expression and MAPK Signaling Pathway in Mouse Neuroblastoma Neuro-2A Cells. Planta Med. (2011) 77(13):1512-8.

국제학술지 7

Kim JH, Park SH, Park SG, Choi JS, Xia Y, Sung JH. The Pivotal Role of Reactive Oxygen Species Generation in the Hypoxia-Induced Stimulation of Adipose-Derived Stem Cells. Stem Cells Dev. (2011) 20(10):1753-61.

국제학술지 8

Park BS, Kim WS, Choi JS, Kim HK, Won JH, Ohkubo F, Fukuoka H. Hair growth stimulated by conditioned medium of adipose-derived stem cells is enhanced by hypoxia: evidence of increased growth factor secretion. Biomedical Research (2010) 31(1):27-34.

국제학술지 9

Lee JS, Park KY, Min HG, Lee SJ, Kim JJ, Choi JS, Kim WS, Cha HJ. Negative regulation of stress-induced matrix metalloproteinase-9 by Sirt1 in skin tissue. Experimental Dermatology (2010) 19(12):1060-6.

국제학술지 10

Lee WH*, Choi JS*, Byun MR, Koo K-T, Shin S, Lee SK, Surh Y-J. Functional inactivation of triosephosphate isomerase through phosphorylation during etoposide-induced apoptosis in HeLa Cells: Potential role of Cdk2. Toxicology (2010) 278(2):224-8. (*: co-first author)

국제학술지 11

Lee WH*, Choi JS*, Kim HY, Park JH, Lee SK, Surh Y-J. Potentiation of etoposide-induced apoptosis in HeLa cells by co-treatment with KG-135, a quality-controlled standardized ginsenoside formulation. Cancer Lett. (2010) 294(1):74-81. (*: co-first author)

국제학술지 12

Kim WS, Yang YJ, Min HG, Song MG, Lee JS, Park KY, Kim JJ, Sung JH, Choi JS, Cha HJ. Accelerated Wound Healing by S-Methylmethionine Sulfonium: Evidence of Dermal Fibroblast Activation via the ERK1/2 Pathway. Pharmacology (2010) 85(2):68-76.

국제학술지 13

Cho SJ, Lee SS, Kim YJ, Park BD, Choi JS, Liu L, Ham YM, Moon Kim B, Lee SK. Xylocydine, a novel Cdk inhibitor, is an effective inducer of apoptosis in hepatocellular carcinoma cells in vitro and in vivo. Cancer Lett. (2010) 287(2):196-206.

국제학술지14

Sun-Ju Lee, Sang Gyu Park, Hyung-Min Chung, Joon-Seok Choi, Dae-Duk Kim, Jong-Hyuk Sung. Antioxidant and anti-melanogenic effect of the novel synthetic hexapeptide (SFKLRY-NH2). International journal of peptide research & therapeutics (2009) 15:281-286.

국제학술지 15

Liu L, Choi JH, Yim H, Choi JS, Park BD, Cho SJ, Lee SK. ATR (AT mutated Rad3 related) activity stabilizes Cdc6 and delays G2/M-phase entry during hydroxyurea-induced S-phase arrest of HeLa cells. Int J Biochem Cell Biol. (2009) 41(6):1410-20.

국제학술지 16

Lee WH, Choi JS, Kim HY, Park JH, Lee SK, Surh YJ. Heat-processed neoginseng, KG-135, down-regulates G1 Cyclin-dependent kinase through the proteasome-mediated pathway in HeLa cells. Oncol Rep. (2009) 21(2):467-74.

국제학술지 17

Lee JH, Lee DH, Lee HS, Choi JS, Kim KW, Hong SS. Deguelin inhibits human hepatocellular carcinoma by antiangiogenesis and apoptosis. Oncol Rep. (2008) 20(1):129-34.

국제학술지 18

Kim WS, Park BS, Kim HK, Park JS, Kim KJ, Choi JS, Chung SJ, Kim DD, Sung JH. Evidence supporting antioxidant action of adipose-derived stem cells: Protection of human dermal fibroblasts from oxidative stress.. Journal of Dermatological Science (2008) 49(2):133-42.

국제학술지 19

Oh YT, Chun KH, Park BD, Choi JS, Lee SK. Regulation of cyclin-dependent kinase inhibitor p21WAF1/CIP1 by protein kinase C δ-mediated phosphorylation. Apoptosis (2007) 12(7):1339-47.

국제학술지 20

Choi JS, Shin S, Jin YH, Yim H, Koo KT, Chun KH, Oh YT, Lee WH, Lee SK. Cyclin-dependent protein kinase 2 activity is required for mitochondrial translocation of Bax and disruption of mitochondrial transmembrane potential during etoposide-induced apoptosis. Apoptosis (2007) 12(7):1229-41.

국제학술지 21

Chun KH, Cho SJ, Choi JS, Kim SH, Kim KW, Lee SK. Differential regulation of splicing, localization and stability of mammalian ARD1235 and ARD1225 isoforms. Biochem. Biophys. Res. Commun. (2007) 353(1):18-25.

국제학술지 22

Ham YM, Lim JH, Na HK, Choi JS, Park BD, Yim H, Lee SK. Ginsenoside-Rh2-Induced Mitochondrial Depolarization and Apoptosis Are Associated with Reactive Oxygen Species- and Ca2+-Mediated c-Jun NH2-Terminal Kinase 1 Activation in HeLa Cells. J Pharmacol Exp Ther. (2006) 319(3):1276-85.

국제학술지 23

Yim H, Hwang IS, Choi JS, Chun KH, Jin YH, Ham YM, Lee KY, Lee SK. Cleavage of Cdc6 by caspase-3 promotes ATM/ATR kinase-mediated apoptosis of HeLa cells. J Cell Biol. (2006) 174(1):77-88.

국제학술지 24

Kim Y, Koo KT, Choi JS, Jin YH, Yim HS, Oh YT, Lee SK. Analysis of cyclin-dependent kinase 2-regulated phosphorylation of stathmin in etoposide-induced apoptotic HeLa cells by two dimensional electrophoresis and mass spectrometry. J. Health Sci. (2005) 51(2):224-232.

국제학술지 25

Ham YM, Choi JS, Chun KH, Joo SH, Lee SK. The c-Jun N-terminal kinase 1 activity is differentially regulated by specific mechanisms during apoptosis. J Biol Chem. (2003) 278(50):50330-7.

국제학술지 26

Jin YH, Choi JS, Shin S, Lee KY, Park JH, Lee SK. Panaxadiol selectively inhibits cyclin A-associated Cdk2 activity by elevating p21WAF1/CIP1 protein levels in mammalian cells. Carcinogenesis. (2003) 24(11):1767-72.

국제학술지 27

Ham YM, Chun KH, Choi JS, Kim DH, Lee SK. SEK1-dependent JNK1 activation prolongs cell survival during G-Rh2-induced apoptosis. Biochem Biophys Res Commun. (2003) 304(2):358-64.