B.S., College of Pharmacy, Catholic University of Daegu
2004–2006
M.S., College of Pharmacy, Catholic University of Daegu
2010–2013
Ph.D., College of Pharmacy, Pusan National University
2006–2008
Research Scientist, Pharmaceutical R&D center, Kyung-Dong Pharm. Co., Ltd
2008–2009
Research Scientist, Pharm. R&D Park, LG Life Sciences Ltd
2013–2014
Post doctoral scholar, Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky
2015-2022
Assistant Professor, Department of Pharmaceutical Engineering, Inje University
2022-2023
Associate Professor, Department of Pharmaceutical Engineering, Inje University
논문 1
D.H. Choi, N.A. Kim, K.R. Chu, Y.J. Jung, J.H. Yoon, S.H. Jeong, Material properties and compressibility using Heckel and Kawakita equation with commonly used pharmaceutical excipients, Journal of Pharmaceutical Investigation 40(4), 237-244, (2010).
논문 2
D.H. Choi, S.H. Jeong, Multi-layered matrix tablets with various tablet designs and release profiles, Journal of Pharmaceutical Investigation 41 (5), 263-272, (2011).
논문 3
D.H. Choi, Y.J. Jung, H.S. Wang, J.H. Yoon, S.H. Jeong, Evaluation of Physical Properties as Magnesium Stearate Blendedin Hydrophilic Matrix Tablets, Journal of Pharmaceutical Investigation 41 (2), 83-90, (2011).
논문 4
S. Shin, D.H. Choi, NKV Truong, N.A. Kim, K.R. Chu, S.H. Jeong, Time-oriented experimental design method to optimize hydrophilic matrix formulations with gelation kinetics and drug release profiles, International journal of pharmaceutics 407 (1-2), 53-62, (2011).
논문 5
D.H. Choi, S. Shin, NK Viet Truong, S.H. Jeong, A new experimental design method to optimize formulations focusing on a lubricant for hydrophilic matrix tablets, Drug Development and Industrial Pharmacy 38 (9), 1117-1127, (2012).
논문 6
D.H. Choi, K.H. Kim, J.S. Park, S.H. Jeong, K. Park, Evaluation of drug delivery profiles in geometric three-layered tablets with various mechanical properties, in vitro–in vivo drug release, and Raman imaging, Journal of Controlled Release 172 (3), 763-772, (2013).
논문 7
N.A. Kim, D.H. Choi, J.Y. Lim, K.H. Kim, D.G. Lim, E. Lee, E.S. Park, S.H. Jeong, Investigation of polymeric excipients for dutasteride solid dispersion and its physicochemical characterization, Archives of pharmacal research 37, 214-224, (2014).
논문 8
D.H. Choi, N.A. Kim, T.S. Nam, S. Lee, S.H. Jeong, Evaluation of taste-masking effects of pharmaceutical sweeteners with an electronic tongue system, Drug Development and Industrial Pharmacy 40 (3), 308-317, (2014).
논문 9
D.H. Choi, D.G. Lim, H.M. Son, S.H. Jeong, Comprehensive evaluation of layer separation tendency of novel three-layered tablets with geometric and mechanical properties, International Journal of Pharmaceutics 465 (1-2), 347-359, (2014).
논문 10
D.H. Choi, J.Y. Lim, S. Shin, W.J. Choi, S.H. Jeong, S. Lee, A novel experimental design method to optimize hydrophilic matrix formulations with drug release profiles and mechanical properties, Journal of Pharmaceutical Sciences 103 (10), 3083-3094, (2014).
논문 11
M. Kwon, D. Yeom, N.A. Kim, D.H. Choi, J. Park, H. Wang, S.D. Yoo, S.H. Jeong, Bioequivalence of tacrolimus formulations with different dynamic solubility and in-vitro dissolution profiles, Archives of pharmacal research 38, 73-80, (2015).
논문 12
E. Csuhai, S. Kangarlou, T.X. Xiang, A. Ponta, P. Bummer, D. H. Choi, Determination of key parameters for a mechanism-based model to predict doxorubicin release from actively loaded liposomes, Journal of pharmaceutical sciences 104 (3), 1087-1098, (2015).
논문 13
KD Fugit, TX Xiang, D.H. Choi, S Kangarlou, E Csuhai, PM Bummer, Mechanistic model and analysis of doxorubicin release from liposomal formulations, Journal of Controlled Release 217, 82-91, (2015).
논문 14
J.Y. Lim, N.A. Kim, D.G. Lim, K.H. Kim, D.H. Choi, S.H. Jeong, Process cycle development of freeze drying for therapeutic proteins with stability evaluation, Journal of Pharmaceutical Investigation 46, 519-536, (2016).
논문 15
Y. Lee, P. Thapa, S.H. Jeong, M.H. Woo, D.H. Choi, Formulation optimization and in vitro characterization of orally disintegrating films using a factorial design and mathematical modeling for drug release, Chemical and Pharmaceutical Bulletin 65 (2), 166-177, (2017).
논문 16
P Thapa, A.R. Lee, D.H. Choi, S.H. Jeong, Effects of moisture content and compression pressure of various deforming granules on the physical properties of tablets, Powder technology 310, 92-102, (2017).
논문 17
Y. Lee, K. Kim, M. Kim, D.H. Choi, S.H. Jeong, Orally disintegrating films focusing on formulation, manufacturing process, and characterization, Journal of Pharmaceutical Investigation 47, 183-201, (2017).
논문 18
T.T. Nguyen, D.H. Nguyen, B.T. Zhao, D.D. Le, D.H. Choi, Y.H. Kim, T.H. Nguyen, A new lignan and a new alkaloid, and α-glucosidase inhibitory compounds from the grains of Echinochloa utilis Ohwi & Yabuno, Bioorganic chemistry 74, 221-227, (2017).
논문 19
A.R. Lee, S.Y. Kwon, D.H. Choi, E.S. Park, Quality by Design (QbD) approach to optimize the formulation of a bilayer combination tablet (Telmiduo®) manufactured via high shear wet granulation, International journal of pharmaceutics 534 (1-2), 144-158, (2017).
논문 20
P. Thapa, R. Thapa, D.H. Choi, S.H. Jeong, Effects of pharmaceutical processes on the quality of ethylcellulose coated pellets: Quality by design approach, Powder technology 339, 25-38, (2018).
논문 21
D.H. Choi, Y.S. Kim, D.D. Kim, S.H. Jeong, QbD based development and evaluation of topical microemulsion-based hydrogel against superficial fungal infections, Journal of Pharmaceutical Investigation 49, 87-103, (2019).
논문 22
P. Thapa, D.H. Choi, M.S. Kim, S.H. Jeong, Effects of granulation process variables on the physical properties of dosage forms by combination of experimental design and principal component analysis, Asian journal of pharmaceutical sciences 14 (3), 287-304, (2019).
논문 23
J.K. Han, B.S. Shin, D.H. Choi, Comprehensive study of intermediate and critical quality attributes for process control of high-shear wet granulation using multivariate analysis and the quality by design approach, Pharmaceutics 11 (6), 252, (2019).
논문 24
S.B. Yeom, D.H. Choi, Scale-up strategy in quality by design approach for pharmaceutical blending process with discrete element method simulation, Pharmaceutics 11 (6), 264, (2019).
논문 25
S.B. Yeom, E.S. Ha, M.S. Kim, S.H. Jeong, S.J. Hwang, D.H. Choi, Application of the discrete element method for manufacturing process simulation in the pharmaceutical industry, Pharmaceutics 11 (8), 414, (2019).
논문 26
E.S. Ha, W.Y. Sim, S.K. Lee, J.S. Jeong, J.S. Kim, I. Baek, D.H. Choi, H. Park
논문 27
D.H. Kuk, E.S. Ha, D.H. Ha, W.Y. Sim, S.K. Lee, J.S. Jeong, J.S. Kim, I. Baek, Development of a resveratrol nanosuspension using the antisolvent precipitation method without solvent removal, based on a quality by design (QbD) approach, Pharmaceutics 11 (12), 688, (2019).
논문 28
N.A. Kim, S. Hong, K.H. Kim, D.H. Choi, J.S. Kim, K.E. Park, J.Y. Choi, Y.K. Shin, New preclinical development of a c-Met inhibitor and its combined anti-tumor effect in c-Met-amplified NSCLC, Pharmaceutics 12 (2), 121, (2020).
논문 29
J.S. Kim, E.S. Ha, H. Park, D.H. Choi, M.S. Kim, I. Baek, Pharmacokinetic Study of a Soft Gelatin Capsule and a Solid-Supersaturatable SMEDDS Tablet of Dutasteride in Beagle Dogs, European Journal of Drug Metabolism and Pharmacokinetics 45, 235-241, (2020).
논문 30
E.S. Ha, S.K. Lee, D.H. Choi, S.H. Jeong, S.J. Hwang, M.S. Kim, Application of diethylene glycol monoethyl ether in solubilization of poorly water-soluble drugs, Journal of Pharmaceutical Investigation 50, 231-250, (2020).
논문 31
E.H. Jang, Y.S. Park, M.S. Kim, D.H. Choi, Model-based scale-up methodologies for pharmaceutical granulation, Pharmaceutics 12 (5), 453, (2020).
논문 32
M.S. Park, D.H. Choi, Application of mechanism-based modeling to predict drug quality during the pharmaceutical unit operations of granulation and compression: A review, Journal of Pharmaceutical Investigation 50, 445-467, (2020).
논문 33
J.Y. Kim, M.H. Chun, D.H. Choi, Control Strategy for Process Development of High-Shear Wet Granulation and Roller Compaction to Prepare a Combination Drug Using Integrated Quality by Design, Pharmaceutics 13 (1), 80, (2021).
논문 34
E.S. Ha, D.H. Choi, I. Baek, H. Park, M.S. Kim, Enhanced Oral Bioavailability of Resveratrol by Using Neutralized Eudragit E Solid Dispersion Prepared via Spray Drying, Antioxidants 10 (1), 90, (2021).
논문 35
I. Baek, H. Back, J. Chae, E.S. Ha, H. Park, D.H. Choi, CE Staatz, M.S. Kim, Pharmacokinetics of eperisone following oral administration in healthy Korean volunteers, Biopharmaceutics & Drug Disposition 42 (2-3), 94-102, (2021).
논문 36
E.H. Jang, Y.S. Park, D.H. Choi, Investigation of the effects of materials and dry granulation process on the mirabegron tablet by integrated QbD approach with multivariate analysis, Powder Technology 382, 23-39, (2021).
논문 37
E.J. Kim, J.H. Kim, M.S. Kim, S.H. Jeong, D.H. Choi, Process analytical technology tools for monitoring pharmaceutical unit operations: a control strategy for continuous process verification, Pharmaceutics 13 (6), 919, (2021).
논문 38
N.A. Kim, S. Hada, D.J. Kim, D.H. Choi, S.H. Jeong, Off-label use of plastic syringes with silicone oil for intravenous infusion bags of antibodies, European Journal of Pharmaceutics and Biopharmaceutics 166, 205-215, (2021).
논문 39
M.H. Chun, J.Y. Kim, E.S. Park, D.H. Choi, Development of a Robust Control Strategy for Fixed-Dose Combination Bilayer Tablets with Integrated Quality by Design, Statistical, and Process Analytical Technology Approach, Pharmaceutics 13 (9), 1443, (2021).
논문 40
S.K. Lee, E.S. Ha, H. Park, J.S. Jeong, H.J. Ryu, Y.J. Pyo, D.H. Choi, M.S. Kim, Measurement and correlation of solubility of lifitegrast in four mixtures of (diethylene glycol monoethyl ether, glycerol, PEG 400, and propylene glycol+ water) from 288.15 K …, Journal of Molecular Liquids 340, 117181, (2021).
논문 41
E.J. Kim, D.H. Choi, Quality by design approach to the development of transdermal patch systems and regulatory perspective, Journal of Pharmaceutical Investigation 51 (6), 669-690, (2021).
논문 42
J.K. Han, J.Y. Kim, D.H. Choi, E.S. Park, A formulation development strategy for dual-release bilayer tablets: An integrated approach of quality by design and a placebo layer, International Journal of Pharmaceutics 618, 121659, (2022).
논문 43
J.Y. Kim, D.H. Choi, Control Strategy for Excipient Variability in the Quality by Design Approach Using Statistical Analysis and Predictive Model: Effect of Microcrystalline Cellulose Variability …, Pharmaceutics 14 (11), 2416, (2022).
논문 44
J.Y. Kim, D.H. Choi, Quality by design approach with multivariate analysis and artificial neural network models to understand and control excipient variability, Journal of Pharmaceutical Investigation, 1-18, (2022).
논문 45
S. Hada, K.J. Na, J. Jeong, D.H. Choi, N.A. Kim, S.H. Jeong, Evaluation of subvisible particles in human immunoglobulin and lipid nanoparticles repackaged from a multi-dose vial using plastic syringes, International Journal of Biological Macromolecules, 123439, (2023).